Cyanuric chloride: decent dehydrating agent for an exclusive and efficient synthesis of kinetically controlled isomaleimides

KP Haval, SB Mhaske, NP Argade

Index: Haval, Kishan P.; Mhaske, Santosh B.; Argade, Narshinha P. Tetrahedron, 2006 , vol. 62, # 5 p. 937 - 942

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Citation Number: 21

Abstract

Starting from maleanilic and maleamic acids, a facile general approach to kinetically controlled isomaleimides has been described for the first time using cyanuric chloride as a dehydrating agent with 85–98% yields. The effect of a variety of substituents present on the aromatic ring in amine and maleic anhydride moiety, on these kinetic/thermodynamic dehydration processes of anilic acids has been also described. Under the same set of ...