General Two??Step Preparation of Chalcones Containing Thiazole

D Tazoo, O Oniga, DS Bohle, Z Chua…

Index: Tazoo, Dagobert; Oniga, Ovidiu; Bohle, D. Scott; Chua, Zhijie; Dongo, Etienne Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 768 - 773

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Abstract

Abstract 2-Aryl-4-methyl-5-acetylthiazoles, which were prepared from arylthioamides and chloroacetylacetone, were treated with 6-substituted-3-formylchromones or arylaldehydes to give a series of eighteen new thiazolylchalcones in good yields. The structures of all the synthesized compounds were characterized by 1 H NMR, 13 C NMR, and ES-MS spectrometry. Additionally, the crystal structures of two of these chalcones were ...

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