Searching for minimum increments of hydrophobic collapse: flexible dinaphthyl carboxylates

LF Newcomb, TS Haque…

Index: Newcomb, Lisa F.; Haque, Tasir S.; Gellman, Samuel H. Journal of the American Chemical Society, 1995 , vol. 117, # 24 p. 6509 - 6519

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Citation Number: 61

Abstract

Abstract: In an effort to identify minimal units of hydrophobically induced folding, we have examined flexible molecules containing two naphthyl moieties connected by a four-atom linker that also bears a carboxyl group. Crystallographic data show that the linkers allow intramolecular edge-to-face association of the naphthyl groups without excessive strain in the backbone. For the carboxylate forms of the dinaphthyl compounds, the occurrence of ...