New methods for the synthesis of 3 (2H)-furanones and 2 (5H)-furanones.

…, S Matsubara, K Oshima, T Hiyama, H Nozaki

Index: Saimoto; Shinoda; Matsubara; Oshima; Hiyama; Nozaki Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 10 p. 3088 - 3092

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Citation Number: 20

Abstract

New procedures for the synthesis of 3 (2H)-furanones and 4-alkoxy-2 (5H)-furanones are reported. Reaction of ketones with the lithium salt of propynal diethyl acetal, followed by treatment of the resulting 4-hydroxy-2-alkynal diethyl acetals with sulfuric acid–methanol, gave 2, 2-disubstituted 3 (2H)-furanones. The action of a polymer reagent Hg/Nafion-H upon 4–hydroxy-2-alkynones produced 2, 2, 5-trisubstituted 3 (2H)-furanones. Reaction of 1, 1, ...