Tetrahedron Letters

Ligand-free copper (Ι)-catalyzed Sonogashira-type coupling of arylboronic acids with terminal alkynes

C Pan, F Luo, W Wang, Z Ye, J Cheng

Index: Pan, Changduo; Luo, Fang; Wang, Wenhui; Ye, Zhishi; Cheng, Jiang Tetrahedron Letters, 2009 , vol. 50, # 35 p. 5044 - 5046

Full Text: HTML

Citation Number: 33

Abstract

An efficient ligand-free CuI-catalyzed Sonogashira-type coupling reaction of arylboronic acids with terminal alkynes under air is described. The electron-deficient alkynes gave the desired cross-coupling products in good yields. Thus, it represents a simple and alternative method for the traditional Sonogashira reaction.

Related Articles:

Copper??Catalyzed Amidation of Acids Using Formamides as the Amine Source

[Xie, Ye-Xiang; Song, Ren-Jie; Yang, Xu-Heng; Xiang, Jian-Nan; Li, Jin-Heng European Journal of Organic Chemistry, 2013 , # 25 p. 5737 - 5742]

… of Terminal Alkynes for the Synthesis of Alk??2??ynamides by Using Palladium??on??Carbon as Efficient, Heterogeneous, Phosphine??Free, and Reusable Catalyst

[Gadge, Sandip T.; Khedkar, Mayur V.; Lanke, Satish R.; Bhanage, Bhalchandra M. Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 2049 - 2056]

More Articles...