Synthesis

A facile, selective preparation of monoketals from pentaerythritol and ketones

MC Murguia, SE Vaillard, RJ Grau

Index: Murguia, Marcelo C.; Vaillard, Santiago E.; Grau, Ricardo J. Synthesis, 2001 , # 7 p. 1093 - 1097

Full Text: HTML

Citation Number: 17

Abstract

Abstract The selective preparation of monoketals 3a-f from pentaerythritol 1 and cyclic, acyclic, aromatic, and aliphatic ketones 2a-f was achieved by a facile method. The extreme polarity and low solubility of pentaerythritol in almost all organic solvents were the main difficulties to be overcome for the preparation of monoketals in good yields and high selectivity. A benzene-dimethylformamide (40: 60) mixture proved to be excellent for the ...

Related Articles:

Synthetic studies on azadirachtin: Construction of the highly functionalized decalin moiety of azadirachtin

[Ishihara, Jun; Yamamoto, Yuuko; Kanoh, Naoki; Murai, Akio Tetrahedron Letters, 1999 , vol. 40, # 23 p. 4387 - 4390]

Synthetic studies on azadirachtin: an efficient asymmetric synthesis of the highly functionalized tricyclic decalin part of azadirachtin

[Yamamoto; Ishihara; Kanoh; Murai Synthesis, 2000 , # 13 p. 1894 - 1906]

Synthesis of novel mimetics of the sialyl Lewis X determinant

[Toepfer; Toepfer, Alexander; Kretzschmar; Kretzschmar, Gerhard; Bartnik; Bartnik, Eckart Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9161 - 9164]

More Articles...