Applied Organometallic Chemistry

Regioselective synthesis of 1, 4??disubstituted triazoles using bis [(L) prolinato??N, O] Zn complex as an efficient catalyst in water as a sole solvent

M Kidwai, A Jain

Index: Kidwai, Mazaahir; Jain, Arti Applied Organometallic Chemistry, 2011 , vol. 25, # 8 p. 620 - 625

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Citation Number: 11

Abstract

Abstract A concise, convenient and mild route for one-pot regioselective synthesis of N-aryl- and N-alkyltriazoles in water as a sole solvent is reported. The methodology involves a three- component reaction comprising aryl/alkyl-alkyne, sodium azide and aryl/alkyl/allyl halide catalyzed by zinc (II) L-prolinate. Prominent features of our protocol are incorporation of transition metal catalyst other than copper, water as the reaction medium, recyclability of ...