Iron-Mediated Electrochemical Reaction of α-Chloroesters with Carbonyl Compounds

M Durandetti, C Meignein, J Périchon

Index: Durandetti, Muriel; Meignein, Clothilde; Perichon, Jacques Organic Letters, 2003 , vol. 5, # 3 p. 317 - 320

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Citation Number: 18

Abstract

To extend the scope of this reaction, various parameters have been extensively investigated. Since the reaction is initiated by insertion of zinc into the halogen−carbon bond, most efforts have been focused on the activation of zinc such as Rieke-Zn, 3 Zn−Cu couple, 4 Zn/Ag-graphite, 5 ultrasound, 6 etc. More recently, sonoelectroreduction of zinc powder has given a highly reactive zinc, which reacts with α-bromoesters or allylic compounds. 7 Another ...