Antiallergic Agents. 2. N-(1H-Tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides

…, K Hanamoto, H Nakai, H Inoue, A Ishida…

Index: Honma; Oda; Hashiyama; Hanamoto; Nakai; Inoue; Ishida; Takeda; Ono; Tsuzurahara Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1499 - 1504

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Citation Number: 20

Abstract

= H, OMe, C1) displayed remarkably high potencies in the rat PCA test on oral administration.'Our attention was next focused on exploring this lead in an effort to enhance the activity. In this paper we describe the synthesis and antiallergic activity of this new series of N-tetrazolylpyridinecarboxamides represented by general structure 1, which bears various substituents on the benzene and pyridine rings.