Enamidines. Versatile vehicles for homologation of carbonyl compounds

AI Meyers, GE Jagdmann Jr

Index: Meyers, A. I.; Jagdmann, G. Erik Journal of the American Chemical Society, 1982 , vol. 104, # 3 p. 877 - 879

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Citation Number: 17

Abstract

Communications to the Editor cyclohexanoneb mCHO 62a a Precursor enamidines 3 were cleaved to product aldehydes by hydrazinolysis with 1, l-dimethylhydrazine (see procedure of ref 9) followed by acid hydrolysis of methiodides obtained from the intermediate dimethyhydrazones (Corey, EJ; Enders, D. Tetrahedron Lett. 1976, 3). Prior to addition to lithiated 2, 2 equiv of HMPA were added at-78" C. This procedure was found ...

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