Tetrahedron

Studies on the synthesis of Strychnos indole alkaloids

…, M Salas, M Amat, M Alvarez, I Morgó, B Adrover

Index: Bosch; Salas; Amat; Alvarez; Morgo; Adrover Tetrahedron, 1991 , vol. 47, # 28 p. 5269 - 5276

Full Text: HTML

Citation Number: 10

Abstract

Tetracycles 3b–d, having the ABCD ring substructure of Strychnos alkaloids and a Nb- (formylmethyl) substituent protected as an oxime or hydrazone derivative, have been prepared by nucleophilic addition of the enolate of indoleacetic ester 1 to pyridinium salts 2b– d followed by acid cyclization. The same one-pot, two-step sequence allowed the preparation of tetracycle 3f, which incorporates an α-methoxyacrylate chain at the ...

Related Articles:

Diamination of olefins: Synthesis, structures and reactivity of osmaimidazolidines

[Muniz, Kilian; Iesato, Atsushi; Nieger, Martin Chemistry - A European Journal, 2003 , vol. 9, # 22 p. 5581 - 5596]

Wittig reactions in water media employing stabilized ylides with aldehydes. Synthesis of α, β-unsaturated esters from mixing aldehydes, α-bromoesters, and Ph3P in …

[Shen, Yanchang; Xin, Yuankang; Zhao, Jianhua Tetrahedron Letters, 1988 , vol. 29, # 47 p. 6119 - 6120]

Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors

[Tsai, Ting-Yueh; Hsu, Tsu; Chen, Chiung-Tong; Cheng, Jai-Hong; Yeh, Teng-Kuang; Chen, Xin; Huang, Chung-Yu; Chang, Chung-Nien; Yeh, Kai-Chia; Hsieh, Su-Huei; Chien, Chia-Hui; Chang, Yi-Wei; Huang, Chih-Hsiang; Huang, Yu-Wen; Huang, Chen-Lung; Wu, Ssu-Hui; Wang, Min-Hsien; Lu, Cheng-Tai; Chao, Yu-Sheng; Jiaang, Weir-Torn Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 6 p. 2388 - 2399]

Synthesis of a novel silicon bearing linker for solid phase synthesis

[Ramage, Robert; Andrews, Martin J. I.; Raphy, Jenny; Wang, Pu Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2403 - 2404]

Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B

[Gooden, David M.; Schmidt, Dawn M.Z.; Pollock, Julie A.; Kabadi, Ami M.; McCafferty, Dewey G. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 10 p. 3047 - 3051]

More Articles...