A convenient procedure for parallel ester hydrolysis
MO Anderson, J Moser, J Sherrill, RK Guy
Index: Anderson, Marc O.; Moser, Jamie; Sherrill, John; Guy, R. Kiplin Synlett, 2004 , # 13 p. 2391 - 2393
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Citation Number: 12
Abstract
Abstract The treatment of alkyl esters with barium hydroxide octahydrate in methanol followed by protonation with anhydrous hydrogen chloride affords carboxylic acids. The procedure does not require aqueous workup and is particularly suitable for parallel synthesis applications.
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[Anderson, Marc O.; Sherrill, John; Madrid, Peter B.; Liou, Ally P.; Weisman, Jennifer L.; DeRisi, Joseph L.; Guy, R. Kiplin Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 2 p. 334 - 343]
[Anderson, Marc O.; Sherrill, John; Madrid, Peter B.; Liou, Ally P.; Weisman, Jennifer L.; DeRisi, Joseph L.; Guy, R. Kiplin Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 2 p. 334 - 343]
[Anderson, Marc O.; Sherrill, John; Madrid, Peter B.; Liou, Ally P.; Weisman, Jennifer L.; DeRisi, Joseph L.; Guy, R. Kiplin Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 2 p. 334 - 343]