Tetrahedron Letters

IBX/I 2-mediated oxidation of alkenes and alkynes in water: a facile synthesis of α-iodoketones

JS Yadav, BVS Reddy, AP Singh, AK Basak

Index: Yadav, Jhillu S.; Subba Reddy, Basi V.; Singh, Ashutosh P.; Basak, Ashok K. Tetrahedron Letters, 2008 , vol. 49, # 41 p. 5880 - 5882

Full Text: HTML

Citation Number: 32

Abstract

The conversion of alkenes into α-iodoketones has been achieved in good yields and with high regioselectivity by means of iodohydrin formation and subsequent oxidation with 2- iodoxybenzoic acid (IBX) under mild conditions. Aromatic alkynes are also converted into their corresponding α-iodoketones under similar conditions.

Related Articles:

Preparation of Aromatic Iodoacetyl Derivatives by Direct Iodination with a Potassium Iodide-Potassium Iodate-Sulfuric Acid System.

[Okamoto, Tsuyoshi; Kakinami, Takaaki; Nishimura, Tetsuo; Irwan-Hermawan; Kajigaeshi, Shoji Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 6 p. 1731 - 1733]

A comparison of reactivity of (EtO) 2P (O) CH2I with related non??phosphorus??containing iodides in the radical iodine atom transfer addition

[Balczewski, Piotr; Bialas, Tomasz; Szadowiak, Aldona Heteroatom Chemistry, 2003 , vol. 14, # 2 p. 186 - 188]

An efficient synthesis of hydantoins via sustainable integration of coupled domino processes

[Gao, Meng; Yang, Yan; Wu, Yan-Dong; Deng, Cong; Cao, Li-Ping; Meng, Xiang-Gao; Wu, An-Xin Organic Letters, 2010 , vol. 12, # 8 p. 1856 - 1859]

More Articles...