Preparation of axially chiral quinolinium salts related to NAD+ models: new investigations of these biomimetic models as 'chiral amide-transferring agents'

…, C Papamicaël, F Marsais, G Dupas, V Levacher

Index: Leleu, Stephane; Papamicael, Cyril; Marsais, Francis; Dupas, Georges; Levacher, Vincent Tetrahedron Asymmetry, 2004 , vol. 15, # 24 p. 3919 - 3928

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Citation Number: 15

Abstract

The general purpose of this work is to investigate the potential of biomimetic NAD+ models as 'nucleophile-transferring agents' with the ultimate motivation to develop new synthetic tools. This first report focuses on the preparation of an axially chiral quinolinium salt 8. A preliminary investigation of these NAD+ analogues as 'chiral amide-transferring agents' is reported herein. The synthesis of the desired quinolinium salt 8 was first attempted via a ...