2-Arylbenzothiazole, benzoxazole and benzimidazole derivatives as fluorogenic substrates for the detection of nitroreductase and aminopeptidase activity in clinically …

M Cellier, OJ Fabrega, E Fazackerley, AL James…

Index: Cellier, Marie; Fabrega, Olivier J.; Fazackerley, Elizabeth; James, Arthur L.; Orenga, Sylvain; Perry, John D.; Salwatura, Vindhya L.; Stanforth, Stephen P. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 9 p. 2903 - 2910

Full Text: HTML

Citation Number: 38

Abstract

Abstract A series of 2-(2-nitrophenyl) benzothiazole 7, 2-(2-nitrophenyl) benzoxazole 10 and 2-(2-nitrophenyl) benzimidazole 13 derivatives have been synthesised and assessed as indicators of nitroreductase activity across a range of clinically important Gram negative and Gram positive bacteria. The majority of Gram negative bacteria produced strongly fluorescent colonies with substrates 7 and 10 whereas fluorescence production in Gram ...

Related Articles:

Tri-lacunary polyoxometalates of Na 8 H [PW 9 O 34] as heterogeneous Lewis base catalysts for Knoevenagel condensation, cyanosilylation and the synthesis of …

[Zhao, Shen; Chen, Yang; Song, Yu-Fei Applied Catalysis A: General, 2014 , vol. 475, p. 140 - 146]

Ligand-free direct C-arylation of heterocycles with aryl halides over a metal-organic framework Cu 2 (BPDC) 2 (BPY) as an efficient and robust heterogeneous catalyst

[Le, Hanh T.N.; Nguyen, Tung T.; Vu, Phuong H.L.; Truong, Thanh; Phan, Nam T.S. Journal of Molecular Catalysis A: Chemical, 2014 , vol. 391, # 1 p. 74 - 82]

Direct arylation of oxazole and benzoxazole with aryl or heteroaryl halides using a palladium–diphosphine catalyst

[Derridj, Fazia; Djebbar, Safia; Benali-Baitich, Ouassini; Doucet, Henri Journal of Organometallic Chemistry, 2008 , vol. 693, # 1 p. 135 - 144]

More Articles...