Journal of the American Chemical Society

Selective detection of the carbohydrate-bound state of concanvalin A at the single molecule level

JJ La Clair

Index: La Clair, James J. Journal of the American Chemical Society, 1997 , vol. 119, # 33 p. 7676 - 7684

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Citation Number: 28

Abstract

The labeling of molecules with charge-transfer dyes, such as 5-(dimethylamino)-1- napthalenesulfonyl (dansyl) chloride, is a powerful tool for examining the solvent shell of attached substances. This investigation describes the synthesis and application of a new charge transfer label, based on trans-1-[p-(N, N-dimethylamino) phenyl]-trans-4-(p- nitrophenyl)-1, 3-butadiene (NND). Unlike many commonly used fluorophores, the ...

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