Current Organic Chemistry

Recent applications of trifluoroacetaldehyde ethyl hemiacetal for the synthesis of trifluoromethylated compounds

Y Gong, K Kato

Index: Gong, Yuefa; Kato, Katsuya Synlett, 2002 , # 3 p. 431 - 434

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Citation Number: 18

Abstract

In this review, recent application of trifluoroacetaldehyde ethyl hemiacetal (TFAE) in the preparation of α-trifluoromethyl alcohols and α-trifluoromethyl amines, especially by the direct regioselective and stereoselective substitution of TFAE and its derivatives like imines