A water-soluble, AIE-active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells

Yinan Wang, Hongming Yao, Jian Zhou, Yuning Hong, Bin Chen, Bolong Zhang, Trevor A. Smith, Wallace W. H. Wong, Zujin Zhao

Index: 10.1002/pola.28943

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Abstract

ABSTRACT A new conjugated polyelectrolyte containing tetraphenylethene units in the backbone is synthesized and characterized. This polyelectrolyte is water-soluble and exhibits aggregation-induced emission (AIE) behavior. It is biocompatible and can be directly used in conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells, providing useful information of cellular morphology and intracellular aggregation or motion. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018 A new conjugated polyelectrolyte containing tetraphenylethene units in the backbone is synthesized and characterized. This polyelectrolyte is water-soluble and exhibits aggregation-induced emission (AIE) behavior. It is biocompatible and can be directly used in conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells, providing useful information of cellular morphology and intracellular aggregation or motion.