Cyclopolyamines: synthesis of cyclospermidines and cyclospermines, analogues of spermidine and spermine

G Brand, MW Hosseini, R Ruppert

Index: Brand, Guy; Hosseini, Mir Wais; Ruppert, Romain Tetrahedron Letters, 1994 , vol. 35, # 46 p. 8609 - 8612

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Citation Number: 20

Abstract

Abstract The synthesis of a series of cyclic analogues of the naturally occurring polyamines putrescine, spermidine and spermine was achieved. The cyclic analogues of putrescine named cycloputrescine [4, n] were composed of cycloputrescine in which the two primary amines were connected with a polymethylene chain of variable length (n= 3, 4, 5). Cyclospermidines [4, n] and Cyclospermines [4, n] were composed of a cycloputrescine [4, ...