Design and Scale-Up of a Practical Enantioselective Route to 5-Phenylbicyclo [2.2. 2] oct-5-en-2-one
S Abele, R Inauen, JA Funel…
Index: Coons, Susanna; Javanmard, Sahar; Collard, David M.; Kuhar, Michael J.; Schweri, Margaret M.; Deutsch, Howard M. Medicinal Chemistry Research, 2002 , vol. 11, # 1 p. 24 - 38
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Abstract
... Select a Journal or Book ... of dimethyl malonate to cyclohexenone 13 catalyzed by (R)-ALB (Al–Li-bis(binaphthoxide complex); without crystallization the crude Michael adduct was ... 1.0 equiv), 10–29 °C, 3 h, toluene-solution of 24 telescoped into next step; (c) 2.4 M LiAlH 4 in ...
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