Tetrahedron

Claisen rearrangements-XIII: Synthesis of the natural coumarins, nordentatin, dentatin and clausarin

RDH Murray, ZD Jorge

Index: Murray, R. D. H.; Jorge, Z. D. Tetrahedron, 1984 , vol. 40, # 16 p. 3133 - 3136

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Citation Number: 9

Abstract

The structure of the natural coumarin, clausarin 10 has been confirmed by an eight-step synthesis from 5-hydroxyseselin 1 in 56%, overall yield. The efficient synthesis of its precursor, nordentatin 5 provides a convenient alternative synthetic route to dentatin 6. The revised structure 13 is suggested for clausenidinaric acid.