Tetrahedron

Cycloadditions and annulations of transition metal carbene complexes

WD Wulff, PC Tang, KS Chan, JS McCallum, DC Yang…

Index: Wulff, William D.; Tang, Peng-Cho; Chan, Kin-Shing; McCallum, J. Stuart; Yang, Dominic C.; Gilbertson, Scott R. Tetrahedron, 1985 , vol. 41, # 24 p. 5813 - 5832

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Citation Number: 108

Abstract

The synthetic aspects of several reactions from the multifaceted chemistry of Fischer carbene complexes are examined. Their benzannulation reactions with acetylenes are utilized in the synthesis of anthracyclinones via two approaches which differ by beginning at opposite ends of the molecule with either an aryl or an alkenyl substituted chromium carbene complex. The latter has been employed in a formal synthesis of daunomycinone. ...