Intramolecular anodic olefin coupling reactions: a new approach to the synthesis of angularly fused, tricyclic enones

LV Tinao-Wooldridge, KD Moeller…

Index: Tinao-Wooldridge, Luzviminda V.; Moeller, Kevin D.; Hudson, Christine M. Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2381 - 2389

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Citation Number: 30

Abstract

A number of intramolecular anodic olefin coupling reactions have been examined in order to determine the feasibility of using a sequential electrochemical oxidation-aldol condensation approach for constructing polycyclic enones. Initially, substrates comprised of an aldehyde enol ether tethered to a ketone enol ether were examined. In a model study, it was shown that such a substrate could lead to a successful electrochemical oxidation-aldol ...