Chemistry Letters

Rapid Access to 3-Aryltetralin Skeleton via C (sp3)-H Bond Functionalization: Investigation on the Substituent Effect of Aromatic Ring Adjacent to CH Bond in Hydride …

K Mori, S Sueoka, T Akiyama

Index: Mori, Keiji; Sueoka, Shosaku; Akiyama, Takahiko Chemistry Letters, 2011 , vol. 40, # 12 p. 1386 - 1388

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Citation Number: 20

Abstract

The concise construction of 3-aryltetralin skeleton via hydride shift mediated C–H bond functionalization was achieved. In this process, the benzylic [1, 5]-H shift occurred smoothly to furnish tetralin derivatives in good to excellent chemical yields. The electronic and steric properties of the aromatic ring adjacent to the C–H bond influenced significantly the reactivity of this transformation.