Iron (II)'hanging imidazole'porphyrin: synthesis and proximal ligand effect on CO and O 2 binding

…, B Loock, D Lavalette, C Tétreau, J Mispelter

Index: Momenteau, Michel; Loock, Bernard; Lavalette, Daniel; Tetreau, Catherine; Mispelter, Joel Journal of the Chemical Society, Chemical Communications, 1983 , # 17 p. 962 - 964

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Citation Number: 23

Abstract

The preparation of the title compound, a model for the active site of oxygen carrier hemoproteins, is described and the kinetic parameters of the CO and O2 adducts show the importance of the co-ordinated imidazole in stabilization. ... The interest in the design of 'hanging base' porphyrins is due to the stepwise changes in the chemical environment on the distal or proximal side of the heme which can be achieved and to their effect on the kinetic rate parameters for ...