Dopaminergic agonists: comparative actions of amine and sulfonium analogs of dopamine

A Hamada, YA Chang, N Uretsky…

Index: Hamada, Akihiko; Chang, Yu An; Uretsky, Norman; Miller, Duane D. Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 675 - 680

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Citation Number: 17

Abstract

7 agonist activity and that sulfonium analogues of dopamine, eg, 4, possess significant activity in both dopamine binding and behavioral~ tudies.~ An important approach toward understanding the conformational requirements for drugs acting on dopamine receptors has been to examine molecules possessing a dopamine segment in structures of conformationally restricted molecules, such as 6, 7-dihydroxy-2-aminotetralin