Organic Letters 2018-04-10

Schincalactones A and B, Two 5/5/6/11/3 Fused Schinortriterpenoids with a 13-Membered Carbon Ring System from Schisandra incarnata

Jian Song, Ming Zhou, Jia Zhou, Jing-Jing Liang, Xiao-Gang Peng, Junjun Liu, Han-Li Ruan

Index: 10.1021/acs.orglett.8b00889

Full Text: HTML

Abstract

Two novel schinortriterpenoids (SNTs), schincalactones A (1) and B (2), featuring a unique 5/5/6/11/3 ring system, together with schincalide B (3), were isolated from Schisandra incarnata. Their structures were elucidated by detailed spectroscopic analysis, and the absolute configurations of 1 and 3 were confirmed by single-crystal X-ray diffraction. Compounds 1 and 2 possess a 13-membered carbon ring and are the first examples in the SNT family. Plausible biosynthetic pathways of 1–3 were postulated.

Latest Articles:

Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.01,5]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme

2018-04-11

[10.1021/acs.orglett.8b00842]

Studies toward the Synthesis of Iriomoteolide-2a: Construction of the C(6)–C(28) Fragment

2018-04-10

[10.1021/acs.orglett.8b00542]

Aroyl Isocyanates as 1,4-Dipoles in a Formal [4 + 1]-Cycloaddition Approach toward Oxazolone Construction

2018-04-10

[10.1021/acs.orglett.8b00656]

Controlled Synthesis of C70 Equatorial Multiadducts with Mixed Addends from an Equatorial Diadduct: Evidence for an Electrophilic Carbanion

2018-04-10

[10.1021/acs.orglett.8b00672]

Nitrate-promoted Selective C–H Fluorination of Benzamides and Benzeneacetamides

2018-04-10

[10.1021/acs.orglett.8b00793]

More Articles...