Alkenyl-copper derivatives 24: Stereospecific synthesis of enones by palladium catalysed acylation of alkenyl-copper reagents

N Jabri, A Alexakis, JF Normant

Index: Jabri, N.; Alexakis, A.; Normant, J. F. Tetrahedron Letters, 1983 , vol. 24, # 46 p. 5081 - 5084

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Citation Number: 21

Abstract

Abstract α, βethylenic ketones and α, β, α′, β′ diethylenic ketones with a stereodefined substitution pattern are easily prepared by coupling of alkenyl copper and cuprate reagents, directly obtained by carbocupration of alkynes, with acid chlorides and anhydrides in the presence of a catalytic amount of Pd complex.