ACS Catalysis 2018-03-30

Pd(II)-Catalyzed Catellani-Type Domino Reaction Utilizing Arylboronic Acids as Substrates

Guangfa Shi, Changdong Shao, Xiaotian Ma, Yichao Gu, Yanghui Zhang

Index: 10.1021/acscatal.8b00637

Full Text: HTML

Abstract

The Catellani reaction provides a facile and efficient method for the synthesis of multifunctionalized arenes. However, the use of Pd(0) catalysts restricts the scope of accessible products. We have developed a Pd(II)-catalyzed, Catellani-type reaction utilizing arylboronic acids as the substrates for the first time. The arylboronic acids can be mono- or dialkylated at the ortho positions with alkyl iodides and olefinated at the ipso positions with olefins, producing various multifunctionalized aromatic compounds. This work should open new avenues for developing novel Catellani reactions, in particular those using new electrophiles.

Latest Articles:

Iron-Catalyzed Direct Olefin Diazidation via Peroxyester Activation Promoted by Nitrogen-Based Ligands

2018-04-19

[10.1021/acscatal.8b00821]

Catalytic Dehydrogenation of (Di)Amine-Boranes with a Geometrically Constrained Phosphine-Borane Lewis Pair

2018-04-18

[10.1021/acscatal.8b00152]

Well-Defined β-Diketiminatocobalt(II) Complexes for Alkene Cyclohydroamination of Primary Amines

2018-04-18

[10.1021/acscatal.8b00631]

Isoprene Regioblock Copolymerization: Switching the Regioselectivity by the in Situ Ancillary Ligand Transmetalation of Active Yttrium Species

2018-04-18

[10.1021/acscatal.8b00600]

Low-Energy Electrocatalytic CO2 Reduction in Water over Mn-Complex Catalyst Electrode Aided by a Nanocarbon Support and K+ Cations

2018-04-18

[10.1021/acscatal.8b01068]

More Articles...