Direct Liquid-Phase Phenol-to-Aniline Amination Using Pd/C
Thomas Cuypers, Patrick Tomkins, Dirk de Vos
Index: 10.1039/C8CY00193F
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Abstract
Here we report the first direct amination of phenol with ammonia into primary anilines in the liquid phase. For this, Pd/C was demonstrated to be the most suitable catalyst. Optimization of the reaction parameters resulted in a very selective and sustainable production of primary anilines with yields up to 95%.
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