Enantioselective Organocatalytic Multicomponent Synthesis of 2, 6??Diazabicyclo [2.2. 2] octanones

…, X Bugaut, T Constantieux, J Rodriguez

Index: Sanchez Duque, Maria Del Mar; Basle, Olivier; Genisson, Yves; Plaquevent, Jean-Christophe; Bugaut, Xavier; Constantieux, Thierry; Rodriguez, Jean Angewandte Chemie - International Edition, 2013 , vol. 52, # 52 p. 14143 - 14146 Angew. Chem., 2013 , vol. 125, # 52 p. 14393 - 14396,4

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Citation Number: 18

Abstract

Multicomponent reactions consist of the combination of at least three different partners in a domino sequence which occurs without any modification of the reaction conditions.[1] They represent powerful multiple bond-forming transformations for the fast construction of complex structures which are not easily synthesized by traditional stepwise strategies.[2] With the increased focus on the preparation of enantiopure compounds, recent efforts ...