Kinetics and mechanism of the Ivanov reaction: reaction of aldehydes and ketones with phenylacetic acid magnesium enediolate

…, M Mladenova, F Gaudemar-Bardone…

Index: Toullec, Jean; Mladenova, Margarita; Gaudemar-Bardone, Francoise; Blagoev, Blagoi Journal of Organic Chemistry, 1985 , vol. 50, # 14 p. 2563 - 2569

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Citation Number: 6

Abstract

Stopped-flow kinetics of the reaction between aldehydes or ketones and the magnesium enediolate of phenylacetic acid in THF are second order at enediolate concentrations M, the formation of a bis (enedio1ate) requires a more complex kinetic equation. Second-order rate constants are reported for the reaction of the enediolate with a number of aldehydes and ketones at 25" C. Entropies of activation for cyclohexanone, benzaldehyde, 2- ...