Unsaturated Amino Acids. IV. Synthesis of Halogen Substituted Allyglycines1, 2

J Shapira, K Dittmer

Index: Shapira,J.; Dittmer,K. Journal of the American Chemical Society, 1960 , vol. 82, p. 1495 - 1497

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Citation Number: 3

Abstract

Discussion Although both hydrobromic and hydrochloric acids could be made to add to the acetylenic bond of propargylglycine by prolonged refluxing in aqueous solution, it was more convenient to prepare the amino acids from the appropriate condensation product. Similar attempts to add concentrated aqueous hydriodic acid were unsuccessful. However, a glacial acetic acid solution of hydrogen iodide was able to accomplish the desired conversion to y ...