Facile Synthesis of Pyrazolo [3, 4??d] pyrimidines and Pyrimido [4, 5??d] pyrimidin??4??one Derivatives

S Babu Katiyar, A Kumar…

Index: Katiyar, Sanjay Babu; Kumar, Arun; Chauhan, Prem M. S. Synthetic Communications, 2006 , vol. 36, # 20 p. 2963 - 2973

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Citation Number: 10

Abstract

Abstract Pyrazolopyrimidine and pyrimidopyrimidine derivatives have shown a wide range of biological activities such as acting as A1 adenosine receptors, kinase insert domain receptor (KDR), Rous sarcoma oncogene (Src), epidermal growth factor receptor (EGFR), antiproliferative, dihydrofolate reductase (DHFR), antimicrobial, antifungal, and lipid peroxidation. Because of this wide range of activities, we have synthesized pyrazolo [3, 4?? ...