Aerobic Transition-Metal-Free Visible-Light Photoredox Indole C-3 Formylation Reaction

X Li, X Gu, Y Li, P Li

Index: Li, Xiang; Gu, Xiangyong; Li, Yongjuan; Li, Pixu ACS Catalysis, 2014 , vol. 4, # 6 p. 1897 - 1900

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Citation Number: 28

Abstract

An aerobic visible-light-promoted indole C-3 formylation reaction catalyzed by Rose Bengal has been developed. This transition-metal-free process employs molecular oxygen as the terminal oxidant and uses TMEDA as the one-carbon source through C–N bond cleavage. The reaction is compatible with a variety of functional groups.