Highly efficient and enantioselective synthesis of L-arylglycines and D-arylglycine amides from biotransformations of nitriles

MX Wang, SJ Lin

Index: Wang, Mei-Xiang; Lin, Shuang-Jun Tetrahedron Letters, 2001 , vol. 42, # 39 p. 6925 - 6927

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Citation Number: 47

Abstract

Under very mild conditions, the Rhodococcus sp. AJ270-catalysed biotransformation of arylglycine nitriles 1, prepared easily from the reaction of substituted benzaldehydes, ammonium chloride and potassium cyanide, proceeded efficiently to produce optically active