Journal of medicinal chemistry

Synthesis of Substituted 2-Phenyl-1, 4-benzothiazin-3 (4H)-ones and their Activity as Inhibitors of 1, 4-Dipyrrolidino-2-butyne

J Krapcho, A Szabo, J Williams

Index: Krapcho,J. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 214 - 216

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Citation Number: 17

Abstract

Yields in reactions with aliphatic aldehydes wrc ycry Ion-(cs, 5 2) while certain other carboiiyl com-poiiiicls (;. e.% pyridiiic.-~-carbo~ aldeliyde, p-dimetltyl-:~ miiiobenzaldcliyde and cycloheptanone) gave uiipiiri-fiablta mixture... Xi1 cxami~ iation of Table TI revealthat all infrartd spectra of Ib exhibit strong peaks near 6 4 arid 6.6 p, hupporting the assignment of DegrawI2 of at) sorption, duci to the triaxiiir ritig iiear 6.40 aiitf