Journal of the American Chemical Society

Studies in the Mechanism of the Mannich Reaction. I. The Reaction of Methylenediamines with 2-Methyl-2-nitro-1-propanol1

GB Butler

Index: Butler Journal of the American Chemical Society, 1956 , vol. 78, p. 482

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Citation Number: 10

Abstract

It has been shown by Lieberman and Wagner2 that methylene-bis-dibenzylamine can serve as an intermediate in the Mannich reaction with antipyrine under anhydrous condition, using dibenzylamine hydrochloride as catalyst. It also has been shown by Johnson3 that the reaction of aliphatic secondary amines with formaldehyde and primary or secondary nitroalkanes produces Mannich-like bases. This author also observed that the same ...