Synthesis and antimicobacterial activity of 2-substituted 4-arylamino-6-methylpyrimidines

AV Erkin, VI Krutikov, EB Smirnova

Index: Erkin; Krutikov; Smirnova Russian Journal of General Chemistry, 2008 , vol. 78, # 10 p. 1944 - 1948

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Abstract

Abstract 2-Substituted 4-arylamino-6-methylpyrimidines were synthesized by stepwise modification of the structure of 6-methyl-2-thiouracyl through the intermediate 2-(ar) alkylthio- 6-methyl-4-chloropyrimidines. Some of the compounds synthesized exhibit expressed antimycobacterial activity.

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