Unsymmetrical diaryl ketones from arenes
DF Taber, MR Sethuraman
Index: Taber, Douglass F.; Sethuraman, Maya R. Journal of Organic Chemistry, 2000 , vol. 65, # 1 p. 254 - 255
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Citation Number: 20
Abstract
Diaryl ketones serve as valuable intermediates in the synthesis of biologically active compounds. The diarylmethane residue has been seen as a component of such medicinal agents as tolcapone, an inhibitor of catecholamine-O-methyl transferase, 1 and the GABA- delivering agent progabide. 2 Usually, such diaryl ketones have been prepared by the aroylation of aryl organometallics (eg, X) B (OH) 2, Y)(CdO) PdI). 3-5 We report here what ...
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