Mechanistic aspects of the oxidation of 1, 3-disubstituted 6-amino-5-nitrosouracils with lead tetraacetate: the formation of pyrimido [5, 4-g] pteridinetetrone 10-oxides

M Sako, S Ohara, K Hirota, K Kano…

Index: Sako, Magoichi; Ohara, Seiji; Hirota, Kosaku; Kano, Keuji; Maki, Yoshifumi; Taylor, Edward C. Journal of Organic Chemistry, 1991 , vol. 56, # 22 p. 6302 - 6306

Full Text: HTML

Citation Number: 3

Abstract

Results Under the reaction conditions previously utilized for the conversion of la, b to 2a, b, 6- amino-1, 3-diphenyl-5-nitrosouracil (IC) was oxidized with LTA in glacial acetic acid to give the 10-oxide 2c in 80% yield, together with a small amount of 4, 6-diphenylfurazano [3, 4-d] pyrimi-dine-5, 7 (4H, 6H)-dione (3c). Reaction of the l, &unsubstituted or 1-or 3- monosubstituted uracils ld,'le: and lf, 9 respectively, with LTA under the same conditions ...

Related Articles:

Ring closure reactions of β-nitroso-, β-acyl-, and β-thiocarbamoyl-α, β-unsaturated sulfilimines. Synthesis of [1, 2, 5] oxadiazolo [3, 4-d]-, isoxazolo [3, 4-d]-, and …

[Matsumoto, Nobuaki; Takahashi, Masahiko Tetrahedron, 2002 , vol. 58, # 50 p. 10073 - 10079]

Ring closure reactions of β-nitroso-, β-acyl-, and β-thiocarbamoyl-α, β-unsaturated sulfilimines. Synthesis of [1, 2, 5] oxadiazolo [3, 4-d]-, isoxazolo [3, 4-d]-, and …

[Matsumoto, Nobuaki; Takahashi, Masahiko Tetrahedron, 2002 , vol. 58, # 50 p. 10073 - 10079]

Synthesis and Applications of [1-15N]-Labeled 4, 6-Dimethyl-4 H-[1, 2, 5] oxadiazolo [3, 4-d] pyrimidine-5, 7-dione 1-Oxide as a Useful Tool for Mechanistic …

[Yoneda, Fumio; Tachibana, Takako; Tanoue, Junko; Yano, Tetsumi; Sakuma, Yoshiharu Heterocycles, 1981 , vol. 15, # 1 p. 341 - 344]

Ring closure reactions of β-nitroso-, β-acyl-, and β-thiocarbamoyl-α, β-unsaturated sulfilimines. Synthesis of [1, 2, 5] oxadiazolo [3, 4-d]-, isoxazolo [3, 4-d]-, and …

[Matsumoto, Nobuaki; Takahashi, Masahiko Tetrahedron, 2002 , vol. 58, # 50 p. 10073 - 10079]

More Articles...