Synthesis of α-iodo-α, β-unsaturated ketones by the reaction of α-silyl-α, β-unsaturated ketones with ICl or ICl AlCl 3

A Alimardanov, E Negishi

Index: Alimardanov, Asaf; Negishi, Ei-ichi Tetrahedron Letters, 1999 , vol. 40, # 20 p. 3839 - 3842

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Citation Number: 34

Abstract

Treatment of α-silyl-α,β-unsaturated enones, readily preparable as regio- and stereodefined compounds in high yields, with either 2 equiv. of ICl or one equiv. each of ICl and AlCl 3 provides the corresponding α-iodo-α,β-unsaturated enones in high yields. ... For a review, see Negishi EJ Organomet. Chem. in press. ... For a synthesis of stereoisomeric mixtures of α-iodo enones in which the ratio is ca. 3, see Ref. 5d. ... Cookies are used by this site. To decline or ...