Synthesis and antianxiety activity of (. omega.-piperazinylalkoxy) indan derivatives

R Kikumoto, A Tobe, H Fukami…

Index: Kikumoto; Tobe; Fukami; Egawa Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 246 - 250

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Citation Number: 12

Abstract

Although benzodiazepine tranquilizers are used with great clinical success in neurosis,'P2 they are poorly effective in obsessional neurosis and they exhibit undesirable muscle- relaxant Recently, novel compounds without the benzodiazepine structure have been tried in the neurosis area with good result^.^^^ Routine pharmacological screening in our laboratories of compounds directed toward new psychotropic agents has shown that some ...