Journal of medicinal chemistry

Hypocholesterolemic 5-methyltetrazole derivatives

RL Buchanan, V Sprancmanis

Index: Buchanan,R.L.; Sprancmanis,V. Journal of Medicinal Chemistry, 1973 , vol. 16, # 2 p. 174 - 175

Full Text: HTML

Citation Number: 11

Abstract

There remains a great need for developing superior agents for the control of hyperlipoproteinemia and associated atherosclerotic disease. This note describes the synthesis and biological evaluation of a number of related compounds that have resulted from our continued interest in 5-substituted tetrazoles as potential hypolipidemic agents.'from the corresponding nitriles 1-7 by standard synthetic methods (see Tables I ...