Novel Solution-and Solid-Phase Syntheses of Heterocyclic Systems

…, A Gegout, S Heulle, T Masquelin

Index: Cabon, Gaelle; Gaucher, Berangere; Gegout, Aline; Heulle, Sophie; Masquelin, Thierry Chimia, 2003 , vol. 57, # 5 p. 248 - 254

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Citation Number: 7

Abstract

Heterocyclic compounds are an attractive source of screening library structures because they possess varied structural diversity and can exhibit potent biological activity. In this context, we present some of our new and versatile approaches to rapid and efficient syntheses of pharmacologically relevant core structures. These include: combination of both solution-and solid-phase processes in the synthesis of pyrazolo [1, 5-a]-[1, 3, 5]-triazin-4- ...