Journal of Organic Chemistry

Synthesis of arylacetylenes. 3, 5-Di-tert-butylphenylacetylene

MS Newman, LF Lee

Index: Newman,M.S.; Lee,L.F. Journal of Organic Chemistry, 1972 , vol. 37, p. 4468 - 4469

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Citation Number: 68

Abstract

In connection with a research program designed to provide molccules of the rotaxane type2 ne required a quantity of 3, S-di-tert-butylphenylacetylene (1). As starting material 3, 5-di-tert- butyltoluene (2) was readily a~ ailable.~ Our first route involved oxidation of 2 to 3, 5-di-tert- butylbenzoic acid (3), which was converted into 3, 5-di-tert-butylacetophenone (4). Hopefully reaction of 4 with phosphorus pentachloride followed by treatment of the dichloride (or ...