Synthesis of Steroidal Methylene Compounds by the Wittig Reaction1

F Sondheimer, R Mechoulam

Index: Sondheimer; Mechoulam Journal of the American Chemical Society, 1957 , vol. 79, p. 5029,5031

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Citation Number: 44

Abstract

The recently discovered reaction between tri-phenylphosphine-alkylidenes of type I11 (obtained from the bromides I by the sequence shown) and carbonyl compounds to produce the corresponding ethylenes IV, the so-called Wittig reaction, has become one of wide scope and utility in synthetic chemistry. 2 We first became interested in the application of this reaction in the steroid field in

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