Cyclization–Carbonylation–Cyclization Coupling Reactions of Propargyl Acetates and Amides with Palladium (II)–Bisoxazoline Catalysts

…, T Kusakabe, H Takayama, M Kimura…

Index: Yasuhara, Sumie; Sasa, Makiko; Kusakabe, Taichi; Takayama, Hiroyuki; Kimura, Masayuki; Mochida, Tomoyuki; Kato, Keisuke Angewandte Chemie - International Edition, 2011 , vol. 50, # 17 p. 3912 - 3915

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Citation Number: 25

Abstract

3 (2H)-Furanones and oxazoles are common structures in a range of important pharmaceuticals.[1] Diaryl ketones are also frequently found in natural products and pharmaceuticals,[2] and they are good precursors for nonsteroidal antiestrogen drugs, such as tamoxifen,[3] and diarylmethyl compounds, such as histamine H1 antagonists,[4a] antitubercular compounds,[4b] and inhibitors of tubulin polymerization.[4c] A variety of ...