Aryl to aryl palladium migration in the Heck and Suzuki coupling of o-halobiaryls

…, A Ibdah, RD McCulla, Q Huang, J Zhao…

Index: Campo, Marino A.; Zhang, Haiming; Yao, Tuanli; Ibdah, Abdellatif; McCulla, Ryan D.; Huang, Qinhua; Zhao, Jian; Jenks, William S.; Larock, Richard C. Journal of the American Chemical Society, 2007 , vol. 129, # 19 p. 6298 - 6307

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Citation Number: 68

Abstract

A novel 1, 4-palladium migration between the o-and o'-positions of biaryls has been observed in organopalladium intermediates derived from o-halobiaryls. The organopalladium intermediates generated by this migration have been trapped either by a Heck reaction employing ethyl acrylate or by Suzuki cross-coupling using arylboronic acids. This palladium migration can be activated or deactivated by choosing the appropriate ...