Constituents of seeds of Brucea javanica. Structures of new bitter principles, yadanziolides A, B, C, yadanziosides F, I, J, and L.

S Yoshimura, T Sakaki, M Ishibashi, T Tsuyuki…

Index: Yoshimura; Sakaki; Ishibashi; et al. Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 9 p. 2673 - 2679

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Citation Number: 36

Abstract

Three new quassinoids and four new quassinoid glycosides were isolated from water- soluble fraction of methanol extract of seeds of Brucea javanica (L.) MERR, known as “Ya- dan-zi” in Chinese folklore and their structures were determined by spectral and chemical means. Yadanziosides F, I, J, and L were demonstrated to have antileukemic activity.